Imjudo® (tremelimumab-actl)

BL 761289

Imjudo® (tremelimumab-actl)

BL 761289

U.S. License Holder:

AstraZeneca AB

Date of License:


Last Update:


approved_indications FDA-Approved Indications

IMJUDO (tremelimumab-actl) is a cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) blocking antibody indicated:

In combination with durvalumab, for the treatment of adult patients with unresectable hepatocellular carcinoma (uHCC);

In combination with durvalumab and platinum-based chemotherapy for the treatment of adult patients with metastatic non-small cell lung cancer (NSCLC) with no sensitizing epidermal growth factor receptor (EGFR) mutation or anaplastic lymphoma kinase (ALK) genomic tumor aberrations.

approved_indications U.S. Patent Litigations


Case No(s):

U.S. Patent Nos.
9,273,135 (Human Monoclonal Antibodies to Programmed Death Ligand 1 (PD-L1) 9,320.811 (Combination of Anti-CTLA4 Antibody with Diverse Therapeutic Regimens for the Synergistic Treatment of Proliferative Diseases)

Bristol-Myers Squibb Co.; ER Squibb & Sons, LLC

AstraZeneca AB; AstraZeneca Pharmaceuticals LP

Stipulated Dismissal



Information contained in the Venable BiologicsHQ database relates to FDA-approved drug products listed in the CDER Purple Book or on the FDA website ( Information relating to FDA licensed products, FDA-approved indications, and aBLA and 505(b)(2) applications is obtained from public sources including the U.S. FDA website ( Information relating to litigations is given only for cases active from January 31, 2010 onward. Information relating to foreign biosimilar / biologics follow-on products approved in Australia, Canada, the E.U., Japan and South Korea is from public sources. Statistics graphics are compiled from information contained in the Venable BiologicsHQ database.


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