Carvykti® (ciltacabtagene autoleucel)

BL 125746

Carvykti® (ciltacabtagene autoleucel)

BL 125746

U.S. License Holder:

Janssen Biotech, Inc.

Date of License:


Last Update:


approved_indications FDA-Approved Indications

CARVYKTI (ciltacabtagene autoleucel) is a B-cell maturation antigen (BCMA)-directed genetically modified autologous T cell immunotherapy indicated for the treatment of adult patients with relapsed or refractory multiple myeloma who have received at least 1 prior line of therapy, including a proteasome inhibitor, an immunomodulatory agent, and are refractory to lenalidomide.

approved_indications Inter Partes Review Proceedings

PTAB Portal

IPR Case No(s):

U.S. Patent No.
9,765,342 (Chimeric Antigen Receptors Targeting B-Cell Maturation Antigen)

Patent Owner
The United States of America as Reprsented by the Seretary of Health and Human Services; 2seventy bio Inc.; bluebird bio, Inc.; Cartesian Therapeutics, Inc.; Thirsty Brook Bioscience, Inc.

Janssen Biotech, Inc.; Janssen Pharmaceutica NV; Legend Biotech Ireland Limited; Legend Biotech USA, Inc.; Nanjing Legend Biotechnology Co., Ltd.

§ 102 Challenge

§ 103 challenge
Y: Claims 1-9, 13, 17, 19

Claim Types Challenged Under § 103
Composition of Matter

§ 103 Challenge Instituted

IPR Status
IPR Not Instituted


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